Koukl received a M.A. in Philosophy of Religion and Ethics from Talbot School of Theology, and also a M.A. in Christian apologetics from Simon Greenleaf School of Law.
In 1993 Koukl founded Stand to Reason, an organization dedicated to training those supporting his Christian viewpoints to defend their faith with "knowledge, wisdom, and character". Stand To Reason produces a weekly radio program, audio podcasts, articles, and video materials, many available on its website. It sponsors mission trips in which students encounter those with opposing points of view, including Mormons and atheists.